Our team strives to understand the processes of angiogenesis, vasculogenesis and neurogenesis in the eye in development, normal physiology and various pathologies. We hope to use the gained knowledge to explore better therapies for human diseases. Specifically, we characterize the functional properties of important angiogenic and antiangiogenic molecules using animal models, cultured cells and molecular approaches. We also utilize the developing mouse eye as a model to explore the fundamental mechanisms of angiogenesis, vasculargenesis and neurogenesis. Furthermore, we try to reveal the basic cellular and molecular mechanisms underlying our findings.